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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c53a7b4764f03164a262bf98b8692d6ee1aa38a684f65db7198ff17a8554e87' 
  AND token = 'kQs8+aW5Zmw2+1ehNAbuMOTCUY6dVAHsxEvT+SdAyVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}