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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ac3da942494c0d9029023925a3cc45cd96b0c6ea1909df69bd96db98e7123b' 
  AND token = '+XEU0W+2D/1oxxZ8LULW7MI55TxTBVzBwzPcTFBoM1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}