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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4883e7c11c7725a6cf1b0f6d441b6c3254c99a92b7778b21d7aa8879f2a797b7' 
  AND token = '7fSPOCw/pAH563bWsMKB/oW3cAsBm0QGsYVCEd8hnok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}