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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44a9acd08aec5aeb85109b5ba2a9de86cd6f15accb6df66b204fe65546f297d' 
  AND token = 'VTytqqyyjV5QZn79KOcSAaOBaPdhoCIcUsjgbuxRrkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}