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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff87be1a0a45b0b1120492638af198053408e4d1f6809e6cfea217e5effa4cdb' 
  AND token = 'OA4ExbG4I0WTGJUKUTNcP0S8JS2xy0c9eELxERyZXt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}