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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736725fbdc1a5db8479d0be4b51fd0a191ce7247b51b93d79ffbc1591cb99825' 
  AND token = 'EOj8U3SH5Dj8y6PddW7RLUwUX7NhxN/fdPTbBrbslEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}