SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0bea4b62d6a6567f36881057b1a192192df5a45c58d69968b1e8c3b544bd3f' 
  AND token = 'X7rSAMMyVUy7kQl6JwxtiNQUTsUBmxOakV6m20i6Sow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}