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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef31cebd8257d98c9805de76d36f505261015ca5d9f12d1bb1551efed660f608' 
  AND token = 'm0pIuZ8X/+vADP++3UUAZrK8cnWV4s0xQpQj4ZS0sCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}