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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49a86a67072fda675d5fb7091ef7bb75862026cfc476b7e2669fba693630a51' 
  AND token = 'F22h3oq0omWvtXsNlVEC/Z+8vTFjBd81mEeCUFim2Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}