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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653e161d3cf32a47fcbc9bc31017a3c66ca51aabf182c420e089929e18fe6f58' 
  AND token = 'QQs/vkU0qXsxoHZSYjd218WsRbrWyXGmMJKaxbytBRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}