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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2d5289ffd9c710acdc829d13a84a0ee1cf878f5905df3f6e4582bc5b43d6c3' 
  AND token = 'sYZ851bwAK9iWtnlo5snJwn6j39GJ7htWXVaekG/iUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}