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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1972b04841beb0284e25e40583a8a2da37dcc7a0e33a52ebe2fa1f733c1e1e1' 
  AND token = 'sedbXKsP71Rvb1h6UugXY748o7Q1AKifq+pi6SyUsqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}