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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b4286c9c5671ffdbb598732ecf28e2f4def06dc85eb181aee5b3d5e0ace5e8' 
  AND token = 'Amr7njfdrnrxWgs+RE6TM3CfWBpthrjD4WkxarAOnNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}