SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d44f93b50b4e92759c146464fc265b4943efcb1c063f4099ce058c79a972ecb' 
  AND token = 'NFxog0AuDUy8XB2uM0DADaLuZZuHAC3KlJxxwtyKUOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}