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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a2713d8c357d6eac428d0f844d2c2fd2ca3d5bc5d38bd6e1913d43867e6fc2d' 
  AND token = '26in6TFKOWrGmwS3cfWanRObMrfKvRLiXMbbVutImWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}