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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250d9abf57b6227974cea33cabe7758695e1e5fe4e707e4da631554b6293b955' 
  AND token = 'of8Ptkq1Vg1Yttc7W+ZbPvkqqiHSSfbpXg0iT/xLaFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}