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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d9dda08005d0510b2a5e378e3c1a3207e0ee00b16607f36e374729cdce5fb3f' 
  AND token = 'PGg3nA/5sfm4A0fRnES009EFFYfn37WShredmVU9ZW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}