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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce69ec401065c2b0cc6b59358424c3e03f1013d7c8f9e445edc045ddf93473ff' 
  AND token = 'xOjSxuvwiW2VKo7XbQkLd1rmnuvJS2KSxzxpXELRCoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}