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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045c1cfbacd61afa57f274a0ecd41f3f8a9558daa4aafee6404d18c4b52d9020' 
  AND token = 'arL/JEoj2s4kPrjQf+u5JioMRVzeVHke0wRyXsh/A98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}