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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918159456ca85cf6030dedaf05a08c472ddf89cfd78b6c441a1ab9c2b01d83e1' 
  AND token = 'IHN9trSEfGRyOLLjxWGpbvtWJy8C3EjUnMzm9/nQvVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}