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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a26299a85ecbcf1d289229fa742ce2869db942229c38657129971b8752820d80' 
  AND token = '+b8e0aFTxu+G/f8VKGuuCY1rrZsyqHMNZW7oUJrxMLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}