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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35ec116dd3ca89e1a50578c2a9205c139986634a3ee40da4b078171b38975ecb' 
  AND token = 'zJRPwXU/bmCymi4HyuI4IMFubxVcMXjU6E8ebUU/3F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}