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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10528ec2544bfb50fde92cd0236dfe12125e9c63e7cc60b148d0621d9b13f4ff' 
  AND token = 'npYi9G5lKExZ8Kb1TI9uDz9+Y9QP3ZUtPYpb0RJcUAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}