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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a72906219f7b822372f2b0ec39f4ee2f495b0b2edf79ef28fc9021b09a712ed' 
  AND token = 'Dijp3MrJQkAoCv1/7DhgA7z+yDX7Vim9qD/JI7n+r3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}