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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b60202aad8a5611c4bdd7c25cbf3142b93a4ca249dc0d363d87f45b47b8da4c' 
  AND token = 'gzOTYZ7PGuaKmtZp2ahuZHtDO34v0ZUv/YduWsiBzAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}