SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64440e4679180ee6558c38516864f22e6d0fa4420a4fbd83602f1846a1e27d1' 
  AND token = '1Z+x57V5gj9dyZgsxPa4y9E8mfGMcN2vGRWeYVUWR1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}