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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb63426c2018e79f33bfef711b54c43dedbca19aa1f36379cdccab524a2cb07' 
  AND token = 'pUb6p7krorSzr0Jun8/9rzMgKq3X8JrSLr7odBv1o84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}