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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f78547cce5a2c71ac4d4dcb9781518634f200992418d33841b9b80888b2d9a' 
  AND token = '5lYoEHCykgGTSXpiRPdx9/QWqo7adIVaJXt7ZxyDE8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}