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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43421c55e31fe14a5396362c19e71faa139619b52a491f149f30aaa2dbfa0da' 
  AND token = 'IJEL1W8ExCOK1iZ/FOqj12apNi9Kh+YMsLaM38PLbo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}