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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'beef9f20b5f23b61ae5a43b87cf8aebf34e151815817f4f12efa2637198c2f96' 
  AND token = '4HyEEONwH1WZ67O3n8jj0+q/OLUrfvjCRK8Fmuw15SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}