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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8972a017e595d2945044b3823852b292266d350f820e32be267f86b8cd57043c' 
  AND token = '1wExiKUew7k96C1OBaQBLbi8YNKE29jP+OLoEIs0UzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}