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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d018b73ee3d423b67fdeed36ca265a34760040ff2e9de605b155643758b5ef' 
  AND token = 'fp55SCP/FbNaCrRvcVcfbvu6zGe4USGXU07VHjwwdKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}