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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2607fb05f508d568e3aafb781a8ceddc2b29f3a2e7a1750cfeee3e63c5628d83' 
  AND token = 'JF1sV6scRAJ1d4KATcZudyiV2GKJfc9H+TMrM3XmTrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}