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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cba12770b7a048ccf6a9941dbefef2ad10964ba2a7ef4c24972fec8b4e53da0' 
  AND token = 'TzRresb7B7UJu0Iv/+sseaz+1a8TN6M8mR1MUfHHLPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}