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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ecf6122bc98f5742695cdb7cc5c8355ab3b8994576c8c0db68da5499e5db49e' 
  AND token = 'VGVdb9FZ+e4vXJJIuv6XlbNNpd+p9zi9WZucySItp7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}