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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af6252fc4f26dbff99a8ced14f1a5baaa99bd68360386c72f5d71e1ecfe58d5' 
  AND token = 'Ay9+FE2llnC2em/tKbeWliz0TAssTHulREAptUSDnDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}