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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40fe271e71c425a5b61024c4e96188f41144b573b69466a6f62ca9b0d17ef9c1' 
  AND token = 'nIySUZ4R7g2kGYYecU+41YhJWBfYmts1p0ASoj/U5WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}