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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4898059a53c6d3786fae77cd252cd2b16ef7299a082e7e7451e60676be05361' 
  AND token = 'QA7KGtCMzvETMh/3LEubKc7Zq0vr3K/nVx1kKIRLkTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}