SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4337a325f83fb7144ee5bb77cf6027b66b0e3fc8e07a8fa09a2cf319f20dc133' 
  AND token = 'F86Te0j1AEPytkbdYBJtaMzyP1t1wyxIlvRM4cworn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}