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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ebfce9fd7f7b45f245a793d244cf735e76ecad05e138b4176f4daa2f814142' 
  AND token = 'zq62juUNY4G6QCuuLb56ysHwyHxr5DbzJpFMGOPcJRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}