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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '914a03ef1d1fc8c5759ed09f9568b77b0475449dd885bf770dbc818038f5e660' 
  AND token = '/jjLpzo7OONMY9iso9TQK4VjmdRsua8ks5RYzceUwRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}