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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3527343033ce5c67fa61d797a9d305227d89e8256c7c7e24563f1675c37a62a' 
  AND token = '6fify0IiTPn3LgJSwFds1iWRIdNLvub9xzRt8IiE2Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}