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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4222a5feb512efb5e8e354dea0763a0ac86d1a37d3ccb85f2ef192cdff9149fe' 
  AND token = 'ct0MHSNY2EiRSOB48WefkJttz7KfoxiKe0O0LfaQZMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}