SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87f4afea13b5c6dd51e46853264e36a9d04cc3a9454a39ed3fdd52118da2742a' 
  AND token = 'HGE27vbgkZyayARsZwPXVy5uCuJfrDnj4FGL+zc1D+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}