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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f08efd2a6b25b80b410bd0d5050b167f28e3d3b54ee57bf7d649b894aaccde3' 
  AND token = 'xjTt/q5WCqg1m1YwHOMW6b4PgV2yZDdr8z5R7eMy7MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}