SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50bf3bf19d89d0c65944a2fe80508f7176265030cff528fe0ab905bb9b8a818f' 
  AND token = 'GzfbuVvXqSpLP180xavU0J9f+rZIdfPnNXWjN9b/9tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}