SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62f1888153e796273fbec1a7b81ddbecda9870f06b37b4567239b48e4727903c' 
  AND token = 'SDKf+vKtsZ5jIKwOfwytEOqprWJb6yWB6ZJo18Dn3b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}