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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621c2f3b8f48ebfc55aa90eded771ada6b13f5658d16f7366a5b24669b781d3e' 
  AND token = 'd8RMuI+mWGG5JUBO+2d3MQuZBPXMdQgia7lrG6f4g6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}