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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95ce12869ac61d105c631313b7bbc345e96b21e3da6dd307fe58e934d4a047b9' 
  AND token = '5+NXL1HFKDiWp4GZAAcYMiuU23VinwlrEJaUVVq61tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}