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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7e059eb34f342fd056e6e0a69e3fa7865b617242283d5949ca208fbf2e0feb' 
  AND token = 'AQQWvu3Vv5QDNbLScQS2QjIwtYEgHHhOevXYBzIiAnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}